Anti-SLC47A1 antibody (500-550 aa) (STJ13102157)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from aa region 500-550 of human SLC47A1 (MATE1) conjugated to an immunogenic carrier protein was used as the antigen.
General Information
| Short Description | Rabbit polyclonal anti-SLC47A1 (500-550 aa) for use in IHC and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB (confirmed by recombinant protein). A dilution of 1: 200 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | SLC47A1 |
| Gene ID | 55244 |
| Uniprot ID | S47A1_HUMAN |
| Immunogen | A synthetic peptide from aa region 500-550 of human SLC47A1 (MATE1) conjugated to an immunogenic carrier protein was used as the antigen. |
| Immunogen Region | 500-550 aa |
| Specificity | Specific for SLC47A1. |
Additional Info
| Function | Multidrug efflux pump that functions as a H(+)/organic cation antiporter. Plays a physiological role in the excretion of cationic compounds including endogenous metabolites, drugs, toxins through the kidney and liver, into urine and bile respectively. Mediates the efflux of endogenous compounds such as creatinine, vitamin B1/thiamine, agmatine and estrone-3-sulfate. May also contribute to regulate the transport of cationic compounds in testis across the blood-testis-barrier (Probable). |
| Protein Name | Multidrug And Toxin Extrusion Protein 1Mate-1Hmate-1Solute Carrier Family 47 Member 1 |
| Database Links | Reactome: R-HSA-425366 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinApical Cell MembraneLocalizes To The Plasma MembraneAt The Brush Border Membranes Of The Proximal Tubules (Kidney) And At The Bile Caniculi (Liver) |
| Alternative Antibody Names | Anti-Multidrug And Toxin Extrusion Protein 1 antibodyAnti-Mate-1 antibodyAnti-Hmate-1 antibodyAnti-Solute Carrier Family 47 Member 1 antibodyAnti-SLC47A1 antibodyAnti-MATE1 antibody |
Information sourced from Uniprot.org