Anti-SLC47A1 antibody (158-208 aa) (STJ193646)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human S47A1 at the amino acid range 158-208
General Information
| Short Description | Rabbit polyclonal anti-Multidrug and toxin extrusion protein 1 (158-208 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SLC47A1 |
| Gene ID | 55244 |
| Uniprot ID | S47A1_HUMAN |
| Immunogen | Synthesized peptide derived from the human S47A1 at the amino acid range 158-208 |
| Immunogen Region | 158-208 aa |
| Specificity | This antibody detects endogenous levels of S47A1 at Human/Mouse/Rat |
Additional Info
| Function | Multidrug efflux pump that functions as a H(+)/organic cation antiporter. Plays a physiological role in the excretion of cationic compounds including endogenous metabolites, drugs, toxins through the kidney and liver, into urine and bile respectively. Mediates the efflux of endogenous compounds such as creatinine, vitamin B1/thiamine, agmatine and estrone-3-sulfate. May also contribute to regulate the transport of cationic compounds in testis across the blood-testis-barrier (Probable). |
| Protein Name | Multidrug And Toxin Extrusion Protein 1Mate-1Hmate-1Solute Carrier Family 47 Member 1 |
| Database Links | Reactome: R-HSA-425366 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinApical Cell MembraneLocalizes To The Plasma MembraneAt The Brush Border Membranes Of The Proximal Tubules (Kidney) And At The Bile Caniculi (Liver) |
| Alternative Antibody Names | Anti-Multidrug And Toxin Extrusion Protein 1 antibodyAnti-Mate-1 antibodyAnti-Hmate-1 antibodyAnti-Solute Carrier Family 47 Member 1 antibodyAnti-SLC47A1 antibodyAnti-MATE1 antibody |
Information sourced from Uniprot.org