Anti-SLC45A2 antibody (Internal Region) (STJ13102180)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from internal of human SLC45A2 conjugated to blue carrier protein was used as the antigen.
General Information
| Short Description | Rabbit polyclonal anti-SLC45A2 (Internal Region) for use in IHC and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB. A dilution of 1: 1000 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | SLC45A2 |
| Gene ID | 51151 |
| Uniprot ID | S45A2_HUMAN |
| Immunogen | A synthetic peptide from internal of human SLC45A2 conjugated to blue carrier protein was used as the antigen. |
| Immunogen Region | Internal Region |
| Specificity | Specific for SLC45A2. |
Additional Info
| Function | Proton-associated glucose and sucrose transporter. May be able to transport also fructose. Expressed at a late melanosome maturation stage where functions as proton/glucose exporter which increase lumenal pH by decreasing glycolysis. Regulates melanogenesis by maintaining melanosome neutralization that is initially initiated by transient OCA2 and required for a proper function of the tyrosinase TYR. |
| Protein Name | Membrane-Associated Transporter ProteinMelanoma Antigen Aim1Protein Aim-1Solute Carrier Family 45 Member 2 |
| Database Links | Reactome: R-HSA-5662702 |
| Cellular Localisation | Melanosome MembraneMulti-Pass Membrane ProteinEnriched In Mature Melanocyte Membrane Subdomains |
| Alternative Antibody Names | Anti-Membrane-Associated Transporter Protein antibodyAnti-Melanoma Antigen Aim1 antibodyAnti-Protein Aim-1 antibodyAnti-Solute Carrier Family 45 Member 2 antibodyAnti-SLC45A2 antibodyAnti-AIM1 antibodyAnti-MATP antibody |
Information sourced from Uniprot.org