| Host: | Rabbit |
| Applications: | IHC/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-SLC39A2 (ECD) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Lyophilised |
| Purification: | IgG purified |
| Dilution Range: | IHC, WB (confirmed by recombinant protein). A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Storage Instruction: | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: | SLC39A2 |
| Gene ID: | 29986 |
| Uniprot ID: | S39A2_HUMAN |
| Immunogen Region: | ECD |
| Specificity: | Specific for SLC39A2. |
| Immunogen: | A synthetic peptide from extracellular domain of human Zinc transporter ZIP2 (SLC39A2, ZIP2) conjugated to an immunogenic carrier protein was used as the antigen. |
| Function | Transporter for the divalent cation Zn(2+). Mediates the influx of Zn(2+) into cells from extracellular space. The Zn(2+) uniporter activity is independent of H(+)-driving force, but is modulated by extracellular pH and membrane potential. Transports also other divalent cations Zn(2+), Cd2(+), Cu2(+), Co2(+) in the order of decreasing affinity, respectively. In the skin, aids in the differentiation of keratinocytes in the epidermis. |
| Protein Name | Zinc Transporter Zip26a1Eti-1Solute Carrier Family 39 Member 2Zrt- And Irt-Like Protein 2Zip-2Hzip2 |
| Database Links | Reactome: R-HSA-442380 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Zinc Transporter Zip2 antibodyAnti-6a1 antibodyAnti-Eti-1 antibodyAnti-Solute Carrier Family 39 Member 2 antibodyAnti-Zrt- And Irt-Like Protein 2 antibodyAnti-Zip-2 antibodyAnti-Hzip2 antibodyAnti-SLC39A2 antibodyAnti-ZIP2 antibody |
Information sourced from Uniprot.org