Anti-SLC39A10 antibody (STJ191653)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from part of the human protein
General Information
| Short Description | Rabbit polyclonal anti-Zinc transporter ZIP10 for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SLC39A10 |
| Gene ID | 57181 |
| Uniprot ID | S39AA_HUMAN |
| Immunogen | Synthesized peptide derived from part of the human protein |
| Specificity | S39AA Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Zinc-influx transporter. When associated with SLC39A6, the heterodimer formed by SLC39A10 and SLC39A6 mediates cellular zinc uptake to trigger cells to undergo epithelial-to-mesenchymal transition (EMT). SLC39A10-SLC39A6 heterodimers play also an essentiel role in initiating mitosis by importing zinc into cells to initiate a pathway resulting in the onset of mitosis. Plays an important for both mature B-cell maintenance and humoral immune responses. When associated with SLC39A10, the heterodimer controls NCAM1 phosphorylation and integration into focal adhesion complexes during EMT. |
| Protein Name | Zinc Transporter Zip10Solute Carrier Family 39 Member 10Zrt- And Irt-Like Protein 10Zip-10 |
| Database Links | Reactome: R-HSA-442380 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinApical Cell MembraneExpressed At The Apical Membranes Of Proximal Tubules In The Kidney |
| Alternative Antibody Names | Anti-Zinc Transporter Zip10 antibodyAnti-Solute Carrier Family 39 Member 10 antibodyAnti-Zrt- And Irt-Like Protein 10 antibodyAnti-Zip-10 antibodyAnti-SLC39A10 antibodyAnti-KIAA1265 antibodyAnti-ZIP10 antibody |
Information sourced from Uniprot.org