Anti-SLC38A5 antibody (STJA0009375)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human SLC38A5
General Information
| Short Description | Rabbit polyclonal anti-Sodium-coupled neutral amino acid transporter 5 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SLC38A5 |
| Gene ID | 92745 |
| Uniprot ID | S38A5_HUMAN |
| Immunogen | Synthesized peptide derived from human SLC38A5 |
| Specificity | This antibody detects endogenous levels of SLC38A5 at Human, Mouse, Rat |
Additional Info
| Function | Symporter that cotransports neutral amino acids and sodium ions, coupled to an H(+) antiporter activity. Releases L-glutamine and glycine from astroglial cells and may participate in the glutamate/GABA-L-glutamine cycle and the NMDA receptors activation. In addition, contributes significantly to L-glutamine uptake in retina, namely in ganglion and Mueller cells therefore, participates in the retinal glutamate-glutamine cycle. The transport activity is pH sensitive and Li(+) tolerant. Moreover functions in both direction and is associated with large uncoupled fluxes of protons. The transport is electroneutral coupled to the cotransport of 1 Na(+) and the antiport of 1 H(+). May have a particular importance for modulation of net hepatic glutamine flux. |
| Protein Name | Sodium-Coupled Neutral Amino Acid Transporter 5Solute Carrier Family 38 Member 5System N Transporter 2 |
| Database Links | Reactome: R-HSA-352230 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinLocalized At Astroglial Membrane |
| Alternative Antibody Names | Anti-Sodium-Coupled Neutral Amino Acid Transporter 5 antibodyAnti-Solute Carrier Family 38 Member 5 antibodyAnti-System N Transporter 2 antibodyAnti-SLC38A5 antibodyAnti-JM24 antibodyAnti-SN2 antibodyAnti-SNAT5 antibodyAnti-PP7194 antibody |
Information sourced from Uniprot.org