Anti-SLC38A1 antibody (N-Term) (STJ13102144)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from n-terminal region of mouse SLC38A1 (Solute carrier family 38 member 1) conjugated to an immunogenic carrier protein was used as the antigen.
General Information
| Short Description | Rabbit polyclonal anti-SLC38A1 (N-Term) for use in IHC and WB in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB (confirmed by recombinant protein). A dilution of 1: 200 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | SLC38A1 |
| Gene ID | 81539 |
| Uniprot ID | S38A1_HUMAN |
| Immunogen | A synthetic peptide from n-terminal region of mouse SLC38A1 (Solute carrier family 38 member 1) conjugated to an immunogenic carrier protein was used as the antigen. |
| Immunogen Region | N-Term |
| Specificity | Specific for SLC38A1. |
Additional Info
| Post Translational Modifications | N-glycosylation plays an important role in the L-glutamine transport. |
| Function | Symporter that cotransports short-chain neutral amino acids and sodium ions from the extraccellular to the intracellular side of the cell membrane. The transport is elctrogenic, pH dependent and driven by the Na(+) electrochemical gradient. Participates in the astroglia-derived glutamine transport into GABAergic interneurons for neurotransmitter GABA de novo synthesis. May also contributes to amino acid transport in placental trophoblasts. Also regulates synaptic plasticity. |
| Protein Name | Sodium-Coupled Neutral Amino Acid Symporter 1Amino Acid Transporter A1N-System Amino Acid Transporter 2Solute Carrier Family 38 Member 1System A Amino Acid Transporter 1System N Amino Acid Transporter 1 |
| Database Links | Reactome: R-HSA-210455Reactome: R-HSA-352230 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinRestricted To The Somatodendritic Compartment Of NeuronsFound In The Cellular Processes Of Neurons In The Developing Brain |
| Alternative Antibody Names | Anti-Sodium-Coupled Neutral Amino Acid Symporter 1 antibodyAnti-Amino Acid Transporter A1 antibodyAnti-N-System Amino Acid Transporter 2 antibodyAnti-Solute Carrier Family 38 Member 1 antibodyAnti-System A Amino Acid Transporter 1 antibodyAnti-System N Amino Acid Transporter 1 antibodyAnti-SLC38A1 antibodyAnti-ATA1 antibodyAnti-NAT2 antibodyAnti-SAT1 antibodyAnti-SNAT1 antibody |
Information sourced from Uniprot.org