• Western blot analysis of lysates from 3T3 cells, primary antibody was diluted at 1:1000, 4°C over night

Anti-SLC35A3 antibody (263-313 aa) (STJ194631)

SKU:
STJ194631

Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-UDP-N-acetylglucosamine transporter (263-313 aa) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SLC35A3
Gene ID: 23443
Uniprot ID: S35A3_HUMAN
Immunogen Region: 263-313 aa
Specificity: This antibody detects endogenous levels of S35A3 at Human/Mouse/Rat
Immunogen: Synthesized peptide derived from the human S35A3 at the amino acid range 263-313
Function Transports diphosphate-N-acetylglucosamine (UDP-GlcNAc) from the cytosol into the lumen of the Golgi apparatus, functioning as an antiporter that exchanges UDP-N-acetyl-alpha-D-glucosamine for UMP. May supply UDP-GlcNAc as substrate for Golgi-resident glycosyltransferases that generate highly branched, multiantennary complex N-glycans and keratan sulfate. However, the exact role of SLC35A3 still needs to be elucidated, it could be a member of a catalytically more efficient multiprotein complex rather than function independently as a single transporter.
Protein Name Udp-N-Acetylglucosamine Transporter
Golgi Udp-Glcnac Transporter
Solute Carrier Family 35 Member A3
Database Links Reactome: R-HSA-5619083
Reactome: R-HSA-727802
Cellular Localisation Golgi Apparatus Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Udp-N-Acetylglucosamine Transporter antibody
Anti-Golgi Udp-Glcnac Transporter antibody
Anti-Solute Carrier Family 35 Member A3 antibody
Anti-SLC35A3 antibody

Information sourced from Uniprot.org

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