Anti-SLC35A3 antibody (263-313 aa) (STJ194631)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human S35A3 at the amino acid range 263-313
General Information
| Short Description | Rabbit polyclonal anti-UDP-N-acetylglucosamine transporter (263-313 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20Β°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SLC35A3 |
| Gene ID | 23443 |
| Uniprot ID | S35A3_HUMAN |
| Immunogen | Synthesized peptide derived from the human S35A3 at the amino acid range 263-313 |
| Immunogen Region | 263-313 aa |
| Specificity | This antibody detects endogenous levels of S35A3 at Human/Mouse/Rat |
Additional Info
| Function | Transports diphosphate-N-acetylglucosamine (UDP-GlcNAc) from the cytosol into the lumen of the Golgi apparatus, functioning as an antiporter that exchanges UDP-N-acetyl-alpha-D-glucosamine for UMP. May supply UDP-GlcNAc as substrate for Golgi-resident glycosyltransferases that generate highly branched, multiantennary complex N-glycans and keratan sulfate. However, the exact role of SLC35A3 still needs to be elucidated, it could be a member of a catalytically more efficient multiprotein complex rather than function independently as a single transporter. |
| Protein Name | Udp-N-Acetylglucosamine TransporterGolgi Udp-Glcnac TransporterSolute Carrier Family 35 Member A3 |
| Database Links | Reactome: R-HSA-5619083Reactome: R-HSA-727802 |
| Cellular Localisation | Golgi Apparatus MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Udp-N-Acetylglucosamine Transporter antibodyAnti-Golgi Udp-Glcnac Transporter antibodyAnti-Solute Carrier Family 35 Member A3 antibodyAnti-SLC35A3 antibody |
Information sourced from Uniprot.org