Anti-SLC35A1 antibody (1-100) (STJ11103817)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal Cmp-Sialic Acid Transporter (1-100) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SLC35A1 |
| Gene ID | 10559 |
| Uniprot ID | S35A1_HUMAN |
| Immunogen Region | 1-100 |
| Immunogen Sequence | MAAPRDNVTLLFKLYCLAVM TLMAAVYTIALRYTRTSDKE LYFSTTAVCITEVIKLLLSV GILAKETGSLGRFKASLREN VLGSPKELLKLSVPSLVYAV |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human SLC35A1 (NP_006407.1). |
Additional Info
| Function | Transports CMP-sialic acid from the cytosol into the Golgi apparatus, functioning as an antiporter that exchanges CMP-sialic acid for CMP. Binds both CMP-sialic acid and free CMP, but has higher affinity for free CMP. Also able to exchange CMP-sialic acid for AMP and UMP. Also mediates the transport of CDP-ribitol. |
| Protein Name | Cmp-Sialic Acid TransporterCmp-Sa-TrCmp-Sia-TrCstSolute Carrier Family 35 Member A1 |
| Database Links | Reactome: R-HSA-4085001Reactome: R-HSA-5619037Reactome: R-HSA-5663020Reactome: R-HSA-727802 |
| Cellular Localisation | Golgi Apparatus MembraneMulti-Pass Membrane ProteinGolgi Apparatus |
| Alternative Antibody Names | Anti-Cmp-Sialic Acid Transporter antibodyAnti-Cmp-Sa-Tr antibodyAnti-Cmp-Sia-Tr antibodyAnti-Cst antibodyAnti-Solute Carrier Family 35 Member A1 antibodyAnti-SLC35A1 antibody |
Information sourced from Uniprot.org