Anti-SLC32A1 antibody (STJA0007307)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human VGAT
General Information
| Short Description | Rabbit polyclonal anti-Vesicular inhibitory amino acid transporter for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SLC32A1 |
| Gene ID | 140679 |
| Uniprot ID | VIAAT_HUMAN |
| Immunogen | Synthesized peptide derived from human VGAT |
| Specificity | This antibody detects endogenous levels of VGAT at Human, Mouse, Rat |
Additional Info
| Function | Antiporter that exchanges vesicular protons for cytosolic 4-aminobutanoate or to a lesser extend glycine, thus allowing their secretion from nerve terminals. The transport is equally dependent on the chemical and electrical components of the proton gradient. May also transport beta-alanine. Acidification of GABAergic synaptic vesicles is a prerequisite for 4-aminobutanoate uptake. |
| Protein Name | Vesicular Inhibitory Amino Acid TransporterGaba And Glycine TransporterSolute Carrier Family 32 Member 1Vesicular Gaba TransporterHviaat |
| Database Links | Reactome: R-HSA-425393Reactome: R-HSA-888590 |
| Cellular Localisation | Cytoplasmic Vesicle MembraneMulti-Pass Membrane ProteinPresynapsePresents In Glycine-Gaba- Or Gaba- And Glycine-Containing Boutons |
| Alternative Antibody Names | Anti-Vesicular Inhibitory Amino Acid Transporter antibodyAnti-Gaba And Glycine Transporter antibodyAnti-Solute Carrier Family 32 Member 1 antibodyAnti-Vesicular Gaba Transporter antibodyAnti-Hviaat antibodyAnti-SLC32A1 antibodyAnti-VGAT antibodyAnti-VIAAT antibody |
Information sourced from Uniprot.org