Anti-SLC2A3 antibody (1-100) [S2MR] (STJ11102002)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal GLUT3 (1-100) antibody for use in WB, IP and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IP/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S2MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:1000-1:4000IP:0.5 Mu g-4 Mu g antibody for 400 Mu g-600 Mu g extracts of whole cellsELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SLC2A3 |
| Gene ID | 6515 |
| Uniprot ID | GTR3_HUMAN |
| Immunogen Region | 1-100 |
| Immunogen Sequence | MGTQKVTPALIFAITVATIG SFQFGYNTGVINAPEKIIKE FINKTLTDKGNAPPSEVLLT SLWSLSVAIFSVGGMIGSFS VGLFVNRFGRRNSMLIVNLL |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human GLUT3/SLC2A3 (P11169). |
Additional Info
| Tissue Specificity | Highly expressed in brain. Expressed in many tissues. |
| Function | Facilitative glucose transporter. Can also mediate the uptake of various other monosaccharides across the cell membrane. Mediates the uptake of glucose, 2-deoxyglucose, galactose, mannose, xylose and fucose, and probably also dehydroascorbate. Does not mediate fructose transport. Required for mesendoderm differentiation. |
| Protein Name | Solute Carrier Family 2 - Facilitated Glucose Transporter Member 3Glucose Transporter Type 3 - BrainGlut-3 |
| Database Links | Reactome: R-HSA-189200Reactome: R-HSA-196836Reactome: R-HSA-6798695Reactome: R-HSA-9022699 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinPerikaryonCell ProjectionLocalized To Densely Spaced Patches Along Neuronal Processes |
| Alternative Antibody Names | Anti-Solute Carrier Family 2 - Facilitated Glucose Transporter Member 3 antibodyAnti-Glucose Transporter Type 3 - Brain antibodyAnti-Glut-3 antibodyAnti-SLC2A3 antibodyAnti-GLUT3 antibody |
Information sourced from Uniprot.org