Anti-SLC2A2 antibody (1-100) [S3MR] (STJ11101403)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal GLUT2 (1-100) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S3MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:1000-1:6000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SLC2A2 |
| Gene ID | 6514 |
| Uniprot ID | GTR2_HUMAN |
| Immunogen Region | 1-100 |
| Immunogen Sequence | MTEDKVTGTLVFTVITAVLG SFQFGYDIGVINAPQQVIIS HYRHVLGVPLDDRKAINNYV INSTDELPTISYSMNPKPTP WAEEETVAAAQLITMLWSLS |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human GLUT2/SLC2A2 (P11168). |
Additional Info
| Tissue Specificity | Liver, insulin-producing beta cell, small intestine and kidney. |
| Post Translational Modifications | N-glycosylated.required for stability and retention at the cell surface of pancreatic beta cells. |
| Function | Facilitative hexose transporter that mediates the transport of glucose, fructose and galactose. Likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells.may comprise part of the glucose-sensing mechanism of the beta cell. May also participate with the Na(+)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney. Also able to mediate the transport of dehydroascorbate. |
| Protein Name | Solute Carrier Family 2 - Facilitated Glucose Transporter Member 2Glucose Transporter Type 2 - LiverGlut-2 |
| Database Links | Reactome: R-HSA-189200Reactome: R-HSA-210745Reactome: R-HSA-422356Reactome: R-HSA-5619098Reactome: R-HSA-8981373 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Solute Carrier Family 2 - Facilitated Glucose Transporter Member 2 antibodyAnti-Glucose Transporter Type 2 - Liver antibodyAnti-Glut-2 antibodyAnti-SLC2A2 antibodyAnti-GLUT2 antibody |
Information sourced from Uniprot.org