Anti-SLC29A1/hENT1 antibody [SAA1893] (STJA0020321)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2a
General Information
| Short Description | Mouse monoclonal Equilibrative Nucleoside Transporter 1 antibody for use in ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SAA1893 |
| Isotype | IgG2a |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Protein A/G purified from cell culture supernatant |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months |
Target Information
| Gene Symbol | SLC29A1 |
| Gene ID | 2030 |
| Uniprot ID | S29A1_HUMAN |
Additional Info
| Post Translational Modifications | Glycosylated. |
| Function | Uniporter involved in the facilitative transport of nucleosides and nucleobases, and contributes to maintaining their cellular homeostasis. Functions as a Na(+)-independent transporter. Involved in the transport of nucleosides such as adenosine, guanosine, inosine, uridine, thymidine and cytidine. Also transports purine nucleobases (hypoxanthine, adenine, guanine) and pyrimidine nucleobases (thymine, uracil). Mediates basolateral nucleoside uptake into Sertoli cells, thereby regulating the transport of nucleosides in testis across the blood-testis barrier. Regulates inosine levels in brown adipocytes tissues (BAT) and extracellular inosine levels, which controls BAT-dependent energy expenditure. |
| Protein Name | Equilibrative Nucleoside Transporter 1Hent1Equilibrative Nitrobenzylmercaptopurine Riboside-Sensitive Nucleoside TransporterEquilibrative Nbmpr-Sensitive Nucleoside TransporterEs Nucleoside TransporterNucleoside Transporter - Es-TypeSolute Carrier Family 29 Member 1 |
| Database Links | Reactome: R-HSA-83936Reactome: R-HSA-9748787Reactome: R-HSA-9755088 |
| Cellular Localisation | Basolateral Cell MembraneMulti-Pass Membrane ProteinApical Cell MembraneCell MembraneLocalized To The Basolateral Membrane Of Sertoli CellsLocalized To The Cell Membrane Of Erythrocytes |
| Alternative Antibody Names | Anti-Equilibrative Nucleoside Transporter 1 antibodyAnti-Hent1 antibodyAnti-Equilibrative Nitrobenzylmercaptopurine Riboside-Sensitive Nucleoside Transporter antibodyAnti-Equilibrative Nbmpr-Sensitive Nucleoside Transporter antibodyAnti-Es Nucleoside Transporter antibodyAnti-Nucleoside Transporter - Es-Type antibodyAnti-Solute Carrier Family 29 Member 1 antibodyAnti-SLC29A1 antibodyAnti-ENT1 antibody |
Information sourced from Uniprot.org