Anti-SLC29A1 antibody (250-300 aa) (STJ13102238)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from aa region 250-300 of human SLC29A1 conjugated to an immunogenic carrier protein was used as the antigen.
General Information
| Short Description | Rabbit polyclonal anti-SLC29A1 (250-300 aa) for use in IHC and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB. A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | SLC29A1 |
| Gene ID | 2030 |
| Uniprot ID | S29A1_HUMAN |
| Immunogen | A synthetic peptide from aa region 250-300 of human SLC29A1 conjugated to an immunogenic carrier protein was used as the antigen. |
| Immunogen Region | 250-300 aa |
| Specificity | Specific for SLC29A1. |
Additional Info
| Post Translational Modifications | Glycosylated. |
| Function | Uniporter involved in the facilitative transport of nucleosides and nucleobases, and contributes to maintaining their cellular homeostasis. Functions as a Na(+)-independent transporter. Involved in the transport of nucleosides such as adenosine, guanosine, inosine, uridine, thymidine and cytidine. Also transports purine nucleobases (hypoxanthine, adenine, guanine) and pyrimidine nucleobases (thymine, uracil). Mediates basolateral nucleoside uptake into Sertoli cells, thereby regulating the transport of nucleosides in testis across the blood-testis barrier. Regulates inosine levels in brown adipocytes tissues (BAT) and extracellular inosine levels, which controls BAT-dependent energy expenditure. |
| Protein Name | Equilibrative Nucleoside Transporter 1Hent1Equilibrative Nitrobenzylmercaptopurine Riboside-Sensitive Nucleoside TransporterEquilibrative Nbmpr-Sensitive Nucleoside TransporterEs Nucleoside TransporterNucleoside Transporter - Es-TypeSolute Carrier Family 29 Member 1 |
| Database Links | Reactome: R-HSA-83936Reactome: R-HSA-9748787Reactome: R-HSA-9755088 |
| Cellular Localisation | Basolateral Cell MembraneMulti-Pass Membrane ProteinApical Cell MembraneCell MembraneLocalized To The Basolateral Membrane Of Sertoli CellsLocalized To The Cell Membrane Of Erythrocytes |
| Alternative Antibody Names | Anti-Equilibrative Nucleoside Transporter 1 antibodyAnti-Hent1 antibodyAnti-Equilibrative Nitrobenzylmercaptopurine Riboside-Sensitive Nucleoside Transporter antibodyAnti-Equilibrative Nbmpr-Sensitive Nucleoside Transporter antibodyAnti-Es Nucleoside Transporter antibodyAnti-Nucleoside Transporter - Es-Type antibodyAnti-Solute Carrier Family 29 Member 1 antibodyAnti-SLC29A1 antibodyAnti-ENT1 antibody |
Information sourced from Uniprot.org