Anti-SLC29A1 antibody (15-64 aa) (STJ96396)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human ENT1 at the amino acid range 15-64
General Information
| Short Description | Rabbit polyclonal anti-Equilibrative nucleoside transporter 1 (15-64 aa) for use in WB and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000ELISA 1:20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SLC29A1 |
| Gene ID | 2030 |
| Uniprot ID | S29A1_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human ENT1 at the amino acid range 15-64 |
| Immunogen Region | 15-64 aa |
| Specificity | ENT1 Polyclonal Antibody detects endogenous levels of ENT1 protein. |
Additional Info
| Post Translational Modifications | Glycosylated. |
| Function | Uniporter involved in the facilitative transport of nucleosides and nucleobases, and contributes to maintaining their cellular homeostasis. Functions as a Na(+)-independent transporter. Involved in the transport of nucleosides such as adenosine, guanosine, inosine, uridine, thymidine and cytidine. Also transports purine nucleobases (hypoxanthine, adenine, guanine) and pyrimidine nucleobases (thymine, uracil). Mediates basolateral nucleoside uptake into Sertoli cells, thereby regulating the transport of nucleosides in testis across the blood-testis barrier. Regulates inosine levels in brown adipocytes tissues (BAT) and extracellular inosine levels, which controls BAT-dependent energy expenditure. |
| Protein Name | Equilibrative Nucleoside Transporter 1Hent1Equilibrative Nitrobenzylmercaptopurine Riboside-Sensitive Nucleoside TransporterEquilibrative Nbmpr-Sensitive Nucleoside TransporterEs Nucleoside TransporterNucleoside Transporter - Es-TypeSolute Carrier Family 29 Member 1 |
| Database Links | Reactome: R-HSA-83936Reactome: R-HSA-9748787Reactome: R-HSA-9755088 |
| Cellular Localisation | Basolateral Cell MembraneMulti-Pass Membrane ProteinApical Cell MembraneCell MembraneLocalized To The Basolateral Membrane Of Sertoli CellsLocalized To The Cell Membrane Of Erythrocytes |
| Alternative Antibody Names | Anti-Equilibrative Nucleoside Transporter 1 antibodyAnti-Hent1 antibodyAnti-Equilibrative Nitrobenzylmercaptopurine Riboside-Sensitive Nucleoside Transporter antibodyAnti-Equilibrative Nbmpr-Sensitive Nucleoside Transporter antibodyAnti-Es Nucleoside Transporter antibodyAnti-Nucleoside Transporter - Es-Type antibodyAnti-Solute Carrier Family 29 Member 1 antibodyAnti-SLC29A1 antibodyAnti-ENT1 antibody |
Information sourced from Uniprot.org