Anti-SLC28A1 antibody (STJ191446)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from part of the human protein
STJ191446
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General Information

Short DescriptionRabbit polyclonal anti-Sodium/nucleoside cotransporter 1/nucleoside cotransporter 1 for use in WB and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/ELISA
HostRabbit
ReactivityHuman/Mouse/Rat
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
Concentration1 mg/mL
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution RangeWB 1:500-2000
ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Storage InstructionStore at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolSLC28A1
Gene ID9154
Uniprot IDS28A1_HUMAN
ImmunogenSynthesized peptide derived from part of the human protein
SpecificityS28A1 Polyclonal Antibody detects endogenous levels of protein.

Additional Info

Post Translational Modifications N-glycosylated. N-glycosylation is required for localization to the plasma membrane and the transporter activity.
Function Sodium and pyrimidine nucleoside symporter of the plasma membrane that imports uridine, thymidine and cytidine into cells by coupling their transport to the transmembrane sodium electrochemical gradient. Also transports adenosine, an atypical substrate transported with high apparent affinity, but low maximum velocity. Therefore, exhibits the transport characteristics of the nucleoside transport system cit or N2 subtype (N2/cit). Involved in renal nucleoside (re)absorption.
Protein Name Sodium/Nucleoside Cotransporter 1
Concentrative Nucleoside Transporter 1
Cnt 1
Hcnt1
Na(+/Nucleoside Cotransporter 1
Sodium-Coupled Nucleoside Transporter 1
Solute Carrier Family 28 Member 1
Database Links Reactome: R-HSA-83936
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Apical Cell Membrane
Alternative Antibody Names Anti-Sodium/Nucleoside Cotransporter 1 antibody
Anti-Concentrative Nucleoside Transporter 1 antibody
Anti-Cnt 1 antibody
Anti-Hcnt1 antibody
Anti-Na(+/Nucleoside Cotransporter 1 antibody
Anti-Sodium-Coupled Nucleoside Transporter 1 antibody
Anti-Solute Carrier Family 28 Member 1 antibody
Anti-SLC28A1 antibody
Anti-CNT1 antibody

Information sourced from Uniprot.org

Citations

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