| Host: |
Rabbit |
| Applications: |
WB/IHC/IF/ELISA |
| Reactivity: |
Human/Rat/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Long-chain fatty acid transport protein 5 (481-530 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:40000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SLC27A5 |
| Gene ID: |
10998 |
| Uniprot ID: |
S27A5_HUMAN |
| Immunogen Region: |
481-530 aa |
| Specificity: |
ACSVL6 Polyclonal Antibody detects endogenous levels of ACSVL6 protein. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from the human SLC27A5 at the amino acid range 481-530 |
| Function | May mediate the import of long-chain fatty acids (LCFA) by facilitating their transport across cell membranes. Also catalyzes the ATP-dependent formation of fatty acyl-CoA using LCFA and very-long-chain fatty acids (VLCFA) as substrates. Mainly functions as a bile acyl-CoA synthetase catalyzing the activation of bile acids via ATP-dependent formation of bile acid CoA thioesters which is necessary for their subsequent conjugation with glycine or taurine. Both primary bile acids (cholic acid and chenodeoxycholic acid) and secondary bile acids (deoxycholic acid and lithocholic acid) are the principal substrates. In vitro, activates 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate ((25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate or THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol. Plays an important role in hepatic fatty acid uptake and bile acid reconjugation and recycling but not in de novo synthesis of bile acids. |
| Protein Name | Long-Chain Fatty Acid Transport Protein 5Fatp-5Fatty Acid Transport Protein 5Bile Acid-Coa LigaseBa-Coa LigaseBalBile Acyl-Coa SynthetaseBacsCholate--Coa LigaseFatty-Acid-Coenzyme A Ligase - Very Long-Chain 3Long-Chain-Fatty-Acid--Coa LigaseSolute Carrier Family 27 Member 5Very Long-Chain Acyl-Coa Synthetase Homolog 2Vlcs-H2Vlcsh2Very Long-Chain Acyl-Coa Synthetase-Related ProteinVlacs-RelatedVlacsr |
| Database Links | Reactome: R-HSA-159418Reactome: R-HSA-193368Reactome: R-HSA-193775 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane ProteinMicrosomeCell Membrane |
| Alternative Antibody Names | Anti-Long-Chain Fatty Acid Transport Protein 5 antibodyAnti-Fatp-5 antibodyAnti-Fatty Acid Transport Protein 5 antibodyAnti-Bile Acid-Coa Ligase antibodyAnti-Ba-Coa Ligase antibodyAnti-Bal antibodyAnti-Bile Acyl-Coa Synthetase antibodyAnti-Bacs antibodyAnti-Cholate--Coa Ligase antibodyAnti-Fatty-Acid-Coenzyme A Ligase - Very Long-Chain 3 antibodyAnti-Long-Chain-Fatty-Acid--Coa Ligase antibodyAnti-Solute Carrier Family 27 Member 5 antibodyAnti-Very Long-Chain Acyl-Coa Synthetase Homolog 2 antibodyAnti-Vlcs-H2 antibodyAnti-Vlcsh2 antibodyAnti-Very Long-Chain Acyl-Coa Synthetase-Related Protein antibodyAnti-Vlacs-Related antibodyAnti-Vlacsr antibodyAnti-SLC27A5 antibodyAnti-ACSB antibodyAnti-ACSVL6 antibodyAnti-FACVL3 antibodyAnti-FATP5 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
