Anti-SLC26A9 antibody (500-660) (STJ11100481)

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STJ11100481
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SLC26A9
Gene ID: 115019
Uniprot ID: S26A9_HUMAN
Immunogen Region: 500-660
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 500-660 of human SLC26A9 (NP_443166.1).
Immunogen Sequence: RNGYALAQVMDTDIYVNPKT YNRAQDIQGIKIITYCSPLY FANSEIFRQKVIAKTGMDPQ KVLLAKQKYLKKQEKRRMRP TQQRRSLFMKTKTVSLQELQ QDFENAPPTDPNNNQTPANG TSVSYITFSPDSSSPAQSEP PASAEAPGEPSDMLASVPPF V
Tissue Specificity Predominantly expressed in lung at the luminal side of the bronchiolar and alveolar epithelium of lung. To a lower extent, also expressed in pancreas and prostate.
Function Ion transporter that can act both as an ion channel and anion exchanger. Mainly acts as a chloride channel, which mediate uncoupled chloride anion transport in an alternate-access mechanism where a saturable binding site is alternately exposed to either one or the other side of the membrane. Also acts as a DIDS- and thiosulfate- sensitive anion exchanger the exchange of chloride for bicarbonate ions across the cell membrane.
Protein Name Solute Carrier Family 26 Member 9
Anion Transporter/Exchanger Protein 9
Database Links Reactome: R-HSA-427601
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Endomembrane System
Localization To The Cell Membrane Is Inhibited By Wnk Kinases (Wnk1
Wnk2
Wnk3 Or Wnk4) In A Kinase-Independent Mechanism
Alternative Antibody Names Anti-Solute Carrier Family 26 Member 9 antibody
Anti-Anion Transporter/Exchanger Protein 9 antibody
Anti-SLC26A9 antibody

Information sourced from Uniprot.org