| Tissue Specificity | Expressed in all tissues tested. Highly expressed in testis, expressed at intermediate level in small intestine and pancreas, and weakly expressed in kidney, spleen, liver, skeletal muscle and heart. |
| Function | Electroneutral antiporter that mediates the transport of adenyl nucleotides through the inner mitochondrial membrane. Originally identified as an ATP-magnesium/inorganic phosphate antiporter, it also acts as a broad specificity adenyl nucleotide antiporter. By regulating the mitochondrial matrix adenyl nucleotide pool could adapt to changing cellular energetic demands and indirectly regulate adenyl nucleotide-dependent metabolic pathways. In vitro, a low activity is also observed with guanyl and pyrimidine nucleotides. May play a role in protecting cells against oxidative stress-induced cell death, by buffering calcium levels in the mitochondrial matrix through the formation of calcium-phosphate precipitates. |
| Protein Name | Mitochondrial Adenyl Nucleotide Antiporter Slc25a24Mitochondrial Atp-Mg/Pi Carrier Protein 1Mitochondrial Ca(2+-Dependent Solute Carrier Protein 1Short Calcium-Binding Mitochondrial Carrier Protein 1Scamc-1Solute Carrier Family 25 Member 24 |
| Cellular Localisation | Mitochondrion Inner MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Mitochondrial Adenyl Nucleotide Antiporter Slc25a24 antibodyAnti-Mitochondrial Atp-Mg/Pi Carrier Protein 1 antibodyAnti-Mitochondrial Ca(2+-Dependent Solute Carrier Protein 1 antibodyAnti-Short Calcium-Binding Mitochondrial Carrier Protein 1 antibodyAnti-Scamc-1 antibodyAnti-Solute Carrier Family 25 Member 24 antibodyAnti-SLC25A24 antibodyAnti-APC1 antibodyAnti-MCSC1 antibodyAnti-SCAMC1 antibody |
Information sourced from Uniprot.org
