Anti-SLC25A24 antibody (1-200) (STJ114031)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SLC25A24 (1-200) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SLC25A24 |
| Gene ID | 29957 |
| Uniprot ID | SCMC1_HUMAN |
| Immunogen Region | 1-200 |
| Immunogen Sequence | MLRWLRDFVLPTAACQDAEQ PTRYETLFQALDRNGDGVVD IGELQEGLRNLGIPLGQDAE EKIFTTGDVNKDGKLDFEEF MKYLKDHEKKMKLAFKSLDK NNDGKIEASEIVQSLQTLGL TISEQQAELILQSIDVDGTM TVDWNEWRDYFLFNPVTDIE EIIRFWKHSTGIDIGDSLTI PDEFTEDEKKSGQWWRQLLA |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human SLC25A24 (NP_037518.3). |
Additional Info
| Tissue Specificity | Expressed in all tissues tested. Highly expressed in testis, expressed at intermediate level in small intestine and pancreas, and weakly expressed in kidney, spleen, liver, skeletal muscle and heart. |
| Function | Electroneutral antiporter that mediates the transport of adenyl nucleotides through the inner mitochondrial membrane. Originally identified as an ATP-magnesium/inorganic phosphate antiporter, it also acts as a broad specificity adenyl nucleotide antiporter. By regulating the mitochondrial matrix adenyl nucleotide pool could adapt to changing cellular energetic demands and indirectly regulate adenyl nucleotide-dependent metabolic pathways. In vitro, a low activity is also observed with guanyl and pyrimidine nucleotides. May play a role in protecting cells against oxidative stress-induced cell death, by buffering calcium levels in the mitochondrial matrix through the formation of calcium-phosphate precipitates. |
| Protein Name | Mitochondrial Adenyl Nucleotide Antiporter Slc25a24Mitochondrial Atp-Mg/Pi Carrier Protein 1Mitochondrial Ca(2+-Dependent Solute Carrier Protein 1Short Calcium-Binding Mitochondrial Carrier Protein 1Scamc-1Solute Carrier Family 25 Member 24 |
| Database Links | |
| Cellular Localisation | Mitochondrion Inner MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Mitochondrial Adenyl Nucleotide Antiporter Slc25a24 antibodyAnti-Mitochondrial Atp-Mg/Pi Carrier Protein 1 antibodyAnti-Mitochondrial Ca(2+-Dependent Solute Carrier Protein 1 antibodyAnti-Short Calcium-Binding Mitochondrial Carrier Protein 1 antibodyAnti-Scamc-1 antibodyAnti-Solute Carrier Family 25 Member 24 antibodyAnti-SLC25A24 antibodyAnti-APC1 antibodyAnti-MCSC1 antibodyAnti-SCAMC1 antibody |
Information sourced from Uniprot.org