Anti-SLC25A23 antibody (1-160) (STJ116564)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SLC25A23 (1-160) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SLC25A23 |
| Gene ID | 79085 |
| Uniprot ID | SCMC3_HUMAN |
| Immunogen Region | 1-160 |
| Immunogen Sequence | MRGSPGDAERRQRWGRLFEE LDSNKDGRVDVHELRQGLAR LGGGNPDPGAQQGISSEGDA DPDGGLDLEEFSRYLQEREQ RLLLMFHSLDRNQDGHIDVS EIQQSFRALGISISLEQAEK ILHSMDRDGTMTIDWQEWRD HFLLHSLENVEDVLYFWKHS |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human SLC25A23 (NP_077008.2). |
Additional Info
| Tissue Specificity | Expressed at low levels in most tissues examined, with highest expression in brain, skeletal muscle and pancreas. |
| Function | Electroneutral antiporter that mediates the transport of adenine nucleotides through the inner mitochondrial membrane. Originally identified as an ATP-magnesium/inorganic phosphate antiporter, it also acts as a broad specificity adenyl nucleotide antiporter. By regulating the mitochondrial matrix adenine nucleotide pool could adapt to changing cellular energetic demands and indirectly regulate adenine nucleotide-dependent metabolic pathways. Also acts as a regulator of mitochondrial calcium uptake and can probably transport trace amounts of other divalent metal cations in complex with ATP. In vitro, a low activity is also observed with guanyl and pyrimidine nucleotides. |
| Protein Name | Mitochondrial Adenyl Nucleotide Antiporter Slc25a23Mitochondrial Atp-Mg/Pi Carrier Protein 2Short Calcium-Binding Mitochondrial Carrier Protein 3Scamc-3Solute Carrier Family 25 Member 23 |
| Database Links | |
| Cellular Localisation | Mitochondrion Inner MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Mitochondrial Adenyl Nucleotide Antiporter Slc25a23 antibodyAnti-Mitochondrial Atp-Mg/Pi Carrier Protein 2 antibodyAnti-Short Calcium-Binding Mitochondrial Carrier Protein 3 antibodyAnti-Scamc-3 antibodyAnti-Solute Carrier Family 25 Member 23 antibodyAnti-SLC25A23 antibodyAnti-APC2 antibodyAnti-MCSC2 antibodyAnti-SCAMC3 antibody |
Information sourced from Uniprot.org