• Immunohistochemistry analysis of SLC25A21 in paraffin-embedded rat kidney tissue using SLC25A21 Rabbit polyclonal antibody (STJ11105232) at a dilution of 1:50 (40x lens). High pressure antigen retrieval was performed with 0. 01 M citrate buffer (pH 6. 0) prior to immunohistochemistry staining.
  • Immunohistochemistry analysis of SLC25A21 in paraffin-embedded human liver tissue using SLC25A21 Rabbit polyclonal antibody (STJ11105232) at a dilution of 1:50 (40x lens). High pressure antigen retrieval was performed with 0. 01 M citrate buffer (pH 6. 0) prior to immunohistochemistry staining.
  • Western blot analysis of lysates from K-562 cells, using SLC25A21 Rabbit polyclonal antibody (STJ11105232) at 1:400 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.

Anti-SLC25A21 antibody (148-247) (STJ11105232)

SKU:
STJ11105232

$151.88 - $705.38
Current Stock:
Host: Rabbit
Applications: WB/IHC
Reactivity: Human/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Mitochondrial 2-Oxodicarboxylate Carrier (148-247) is suitable for use in Western Blot and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:100-1:500
IHC-P 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SLC25A21
Gene ID: 89874
Uniprot ID: ODC_HUMAN
Immunogen Region: 148-247
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 148-247 of human SLC25A21 (NP_085134.1).
Immunogen Sequence: PSTVGYARQIIKKEGWGLQG LNKGLTATLGRHGVFNMVYF GFYYNVKNMIPVNKDPILEF WRKFGIGLLSGTIASVINIP FDVAKSRIQGPQPVPGEIKY
Tissue Specificity Expressed in placenta, gall bladder and colon.
Function Transports dicarboxylates across the inner membranes of mitochondria by a counter-exchange mechanism. Can transport 2-oxoadipate (2-oxohexanedioate), 2-oxoglutarate, adipate (hexanedioate), glutarate, and to a lesser extent, pimelate (heptanedioate), 2-oxopimelate (2-oxoheptanedioate), 2-aminoadipate (2-aminohexanedioate), oxaloacetate, and citrate. Plays a central role in catabolism of lysine, hydroxylysine, and tryptophan, by transporting common metabolite intermediates (such as 2-oxoadipate) into the mitochondria, where it is converted into acetyl-CoA and can enter the citric acid (TCA) cycle (Probable).
Protein Name Mitochondrial 2-Oxodicarboxylate Carrier
Odc
Mitochondrial 2-Oxoadipate Carrier
Solute Carrier Family 25 Member 21
Database Links Reactome: R-HSA-71064
Cellular Localisation Mitochondrion Inner Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Mitochondrial 2-Oxodicarboxylate Carrier antibody
Anti-Odc antibody
Anti-Mitochondrial 2-Oxoadipate Carrier antibody
Anti-Solute Carrier Family 25 Member 21 antibody
Anti-SLC25A21 antibody
Anti-ODC antibody

Information sourced from Uniprot.org

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