| Host: |
Rabbit |
| Applications: |
WB/IF |
| Reactivity: |
Human/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SLC25A20 (1-301) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:100-1:500IF/ICC 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SLC25A20 |
| Gene ID: |
788 |
| Uniprot ID: |
MCAT_HUMAN |
| Immunogen Region: |
1-301 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 1-301 of human SLC25A20 (NP_000378.1). |
| Immunogen Sequence: |
MADQPKPISPLKNLLAGGFG GVCLVFVGHPLDTVKVRLQT QPPSLPGQPPMYSGTFDCFR KTLFREGITGLYRGMAAPII GVTPMFAVCFFGFGLGKKLQ QKHPEDVLSYPQLFAAGMLS GVFTTGIMTPGERIKCLLQI QASSGESKYTGTLDCAKKLY QEFGIRGIYKGTVLTLMRDV PASGMYFMTYEWLKNIFTPE GKRVSELSAPRILVAGGIAG IFNWAVAIPPDVLKSRFQT |
| Function | Mediates the electroneutral exchange of acylcarnitines (O-acyl-(R)-carnitine or L-acylcarnitine) of different acyl chain lengths (ranging from O-acetyl-(R)-carnitine to long-chain O-acyl-(R)-carnitines) with free carnitine ((R)-carnitine or L-carnitine) across the mitochondrial inner membrane, via a ping-pong mechanism (Probable). Key player in the mitochondrial oxidation pathway, it translocates the fatty acids in the form of acylcarnitines into the mitochondrial matrix, where the carnitine palmitoyltransferase 2 (CPT-2) activates them to undergo fatty acid beta-oxidation (Probable). Catalyzes the unidirectional transport (uniport) of carnitine at lower rates than the antiport (exchange). |
| Protein Name | Mitochondrial Carnitine/Acylcarnitine Carrier ProteinCarnitine/Acylcarnitine TranslocaseCacCactSolute Carrier Family 25 Member 20 |
| Database Links | Reactome: R-HSA-200425 |
| Cellular Localisation | Mitochondrion Inner MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Mitochondrial Carnitine/Acylcarnitine Carrier Protein antibodyAnti-Carnitine/Acylcarnitine Translocase antibodyAnti-Cac antibodyAnti-Cact antibodyAnti-Solute Carrier Family 25 Member 20 antibodyAnti-SLC25A20 antibodyAnti-CAC antibodyAnti-CACT antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
