Anti-SLC25A12 antibody (600-678aa) [SRM13151] (STJ11107881)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 600-678 of human SLC25A12 (NP_003696.2).
General Information
| Short Description | Rabbit monoclonal Electrogenic Aspartate/Glutamate antiporter Slc25a12-Mitochondrial (600-678aa) antibody for use in WB, IHC-P, IP and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IP/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SRM13151 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB, 1:500-1:1000IHC-P, 1:400-1:1600IP, 0.5 Mu g-4 Mu g antibody for 400 Mu g-600 Mu g extracts of whole cellsELISA, Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay require |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SLC25A12 |
| Gene ID | 8604 |
| Uniprot ID | S2512_HUMAN |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 600-678 of human SLC25A12 (NP_003696.2). |
| Immunogen Region | 600-678aa |
| Immunogen Sequence | Human |
Additional Info
| Function | Mitochondrial electrogenic aspartate/glutamate antiporter that favors efflux of aspartate and entry of glutamate and proton within the mitochondria as part of the malate-aspartate shuttle. Also mediates the uptake of L-cysteinesulfinate (3-sulfino-L-alanine) by mitochondria in exchange of L-glutamate and proton. Can also exchange L-cysteinesulfinate with aspartate in their anionic form without any proton translocation. Lacks transport activity towards L-glutamine or gamma-aminobutyric acid (GABA). |
| Protein Name | Electrogenic Aspartate/Glutamate Antiporter Slc25a12 - MitochondrialAraceli HiperlargaAralarAralar1Mitochondrial Aspartate Glutamate Carrier 1Solute Carrier Family 25 Member 12 |
| Database Links | Reactome: R-HSA-1268020Reactome: R-HSA-8963693Reactome: R-HSA-9856872 |
| Cellular Localisation | Mitochondrion Inner MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Electrogenic Aspartate/Glutamate Antiporter Slc25a12 - Mitochondrial antibodyAnti-Araceli Hiperlarga antibodyAnti-Aralar antibodyAnti-Aralar1 antibodyAnti-Mitochondrial Aspartate Glutamate Carrier 1 antibodyAnti-Solute Carrier Family 25 Member 12 antibodyAnti-SLC25A12 antibodyAnti-AGC1 antibodyAnti-ARALAR1 antibody |
Information sourced from Uniprot.org