| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Tricarboxylate transport protein, mitochondrial is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SLC25A1 |
| Gene ID: | 6576 |
| Uniprot ID: | TXTP_HUMAN |
| Specificity: | This antibody detects endogenous levels of SLC25A1 at Human, Rat |
| Immunogen: | Synthesized peptide derived from human SLC25A1 |
| Function | Mitochondrial electroneutral antiporter that exports citrate from the mitochondria into the cytosol in exchange for malate. Also able to mediate the exchange of citrate for isocitrate, phosphoenolpyruvate, cis-aconitate and to a lesser extend cis-aconitate, maleate and succinate. In the cytoplasm citrate is important in the regulation of glycolysis through a feedback mechanism and in the production of acetyl-CoA which is needed for the synthesis of fatty acids, sterols, prostaglandins, dolichol and coenzyme Q (CoQ). Required for proper neuromuscular junction formation (Probable). |
| Protein Name | Tricarboxylate Transport Protein - Mitochondrial Citrate Transport Protein Ctp Mitochondrial Citrate Carrier Cic Solute Carrier Family 25 Member 1 Tricarboxylate Carrier Protein |
| Database Links | Reactome: R-HSA-428643 |
| Cellular Localisation | Mitochondrion Inner Membrane Multi-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Tricarboxylate Transport Protein - Mitochondrial antibody Anti-Citrate Transport Protein antibody Anti-Ctp antibody Anti-Mitochondrial Citrate Carrier antibody Anti-Cic antibody Anti-Solute Carrier Family 25 Member 1 antibody Anti-Tricarboxylate Carrier Protein antibody Anti-SLC25A1 antibody Anti-SLC20A3 antibody |
Information sourced from Uniprot.org