Anti-SLC24A4 antibody (200-300) (STJ119363)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SLC24A4 (200-300) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SLC24A4 |
| Gene ID | 123041 |
| Uniprot ID | NCKX4_HUMAN |
| Immunogen Region | 200-300 |
| Immunogen Sequence | WWAVCRDSVYYTISVIVLIV FIYDEQIVWWEGLVLIILYV FYILIMKYNVKMQAFFTVKQ KSIANGNPVNSELEAGNDFY DGSYDDPSVPLLGQVKEKPQ Y |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 200-300 of human SLC24A4 (NP_705932.2). |
Additional Info
| Tissue Specificity | Expressed abundantly in all regions of the brain, aorta, lung and thymus. Expressed at lower levels in the stomach and intestine. |
| Function | Calcium, potassium:sodium antiporter that transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+). Controls the rapid response termination and proper regulation of adaptation in olfactory sensory neurons (OSNs) which subsequently influences how odor information is encoded and perceived. May play a role in calcium transport during amelogenesis. |
| Protein Name | Sodium/Potassium/Calcium Exchanger 4Na(+/K(+/Ca(2+-Exchange Protein 4Solute Carrier Family 24 Member 4 |
| Database Links | Reactome: R-HSA-425561Reactome: R-HSA-5619055 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinCytoplasm |
| Alternative Antibody Names | Anti-Sodium/Potassium/Calcium Exchanger 4 antibodyAnti-Na(+/K(+/Ca(2+-Exchange Protein 4 antibodyAnti-Solute Carrier Family 24 Member 4 antibodyAnti-SLC24A4 antibodyAnti-NCKX4 antibody |
Information sourced from Uniprot.org