Anti-SLC22A14 antibody (STJA0009373)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human SLC22A14
General Information
| Short Description | Rabbit polyclonal anti-Solute carrier family 22 member 14 for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SLC22A14 |
| Gene ID | 9389 |
| Uniprot ID | S22AE_HUMAN |
| Immunogen | Synthesized peptide derived from human SLC22A14 |
| Specificity | This antibody detects endogenous levels of SLC22A14 at Human |
Additional Info
| Function | Riboflavin transporter localized at the inner mitochondrial membrane of the spermatozoa midpiece, which is required for male fertility. SLC22A14-mediated riboflavin transport is essential for spermatozoa energy generation and motility: riboflavin is the precursor of FMN and FAD, which are coenzymes of many enzymes in the TCA cycle (the citric acid cycle) in mitochondria. Required for sperm motility and normal sperm flagellar structure. |
| Protein Name | Solute Carrier Family 22 Member 14Organic Cation Transporter-Like 4Orctl-4 |
| Database Links | |
| Cellular Localisation | Mitochondrion Inner MembraneMulti-Pass Membrane ProteinCell ProjectionCiliumFlagellum MembraneLocalizes To The Principle Piece Of The Sperm Tail |
| Alternative Antibody Names | Anti-Solute Carrier Family 22 Member 14 antibodyAnti-Organic Cation Transporter-Like 4 antibodyAnti-Orctl-4 antibodyAnti-SLC22A14 antibodyAnti-OCTL2 antibodyAnti-ORCTL4 antibody |
Information sourced from Uniprot.org