| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SLC20A2 (235-485) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SLC20A2 |
| Gene ID: |
6575 |
| Uniprot ID: |
S20A2_HUMAN |
| Immunogen Region: |
235-485 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 235-485 of human SLC20A2 (NP_001244110.1). |
| Immunogen Sequence: |
CPWMRRKITGKLQKEGALSR VSDESLSKVQEAESPVFKEL PGAKANDDSTIPLTGAAGET LGTSEGTSAGSHPRAAYGRA LSMTHGSVKSPISNGTFGFD GHTRSDGHVYHTVHKDSGLY KDLLHKIHIDRGPEEKPAQE SNYRLLRRNNSYTCYTAAIC GLPVHATFRAADSSAPEDSE KLVGDTVSYSKKRLRYDSYS SYCNAVAEAEIEAEEGGVEM KLASELADPDQPREDPAEE |
| Tissue Specificity | Ubiquitously expressed. |
| Function | Sodium-phosphate symporter which preferentially transports the monovalent form of phosphate with a stoichiometry of two sodium ions per phosphate ion. Plays a critical role in the determination of bone quality and strength by providing phosphate for bone mineralization. Required to maintain normal cerebrospinal fluid phosphate levels. Mediates phosphate-induced calcification of vascular smooth muscle cells (VCMCs) and can functionally compensate for loss of SLC20A1 in VCMCs. (Microbial infection) Functions as a retroviral receptor and confers human cells susceptibility to infection to amphotropic murine leukemia virus (A-MuLV), 10A1 murine leukemia virus (10A1 MLV) and some feline leukemia virus subgroup B (FeLV-B) variants. |
| Protein Name | Sodium-Dependent Phosphate Transporter 2Gibbon Ape Leukemia Virus Receptor 2Glvr-2Phosphate Transporter 2Pit-2Pit2Hpit2Solute Carrier Family 20 Member 2 |
| Database Links | Reactome: R-HSA-427652Reactome: R-HSA-5619111 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinApical Cell Membrane |
| Alternative Antibody Names | Anti-Sodium-Dependent Phosphate Transporter 2 antibodyAnti-Gibbon Ape Leukemia Virus Receptor 2 antibodyAnti-Glvr-2 antibodyAnti-Phosphate Transporter 2 antibodyAnti-Pit-2 antibodyAnti-Pit2 antibodyAnti-Hpit2 antibodyAnti-Solute Carrier Family 20 Member 2 antibodyAnti-SLC20A2 antibodyAnti-GLVR2 antibodyAnti-PIT2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
