Anti-SLC20A1 antibody (Internal Region) (STJ13102177)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from internal region of human Sodium-dependent phosphate transporter 1 (SLC20A1, GLVR1) conjugated to an immunogenic carrier protein was used as the antigen.
General Information
| Short Description | Rabbit polyclonal anti-SLC20A1 (Internal Region) for use in IHC and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB (confirmed by recombinant protein). A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | SLC20A1 |
| Gene ID | 6574 |
| Uniprot ID | S20A1_HUMAN |
| Immunogen | A synthetic peptide from internal region of human Sodium-dependent phosphate transporter 1 (SLC20A1, GLVR1) conjugated to an immunogenic carrier protein was used as the antigen. |
| Immunogen Region | Internal Region |
| Specificity | Specific for SLC20A1. |
Additional Info
| Function | Sodium-phosphate symporter which preferentially transports the monovalent form of phosphate with a stoichiometry of two sodium ions per phosphate ion. May play a role in extracellular matrix and cartilage calcification as well as in vascular calcification. Essential for cell proliferation but this function is independent of its phosphate transporter activity. (Microbial infection) May function as a retroviral receptor as it confers human cells susceptibility to infection to Gibbon Ape Leukemia Virus (GaLV), Simian sarcoma-associated virus (SSAV) and Feline leukemia virus subgroup B (FeLV-B) as well as 10A1 murine leukemia virus (10A1 MLV). |
| Protein Name | Sodium-Dependent Phosphate Transporter 1Gibbon Ape Leukemia Virus Receptor 1Glvr-1Leukemia Virus Receptor 1 HomologPhosphate Transporter 1Pit-1Solute Carrier Family 20 Member 1 |
| Database Links | Reactome: R-HSA-427652 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Sodium-Dependent Phosphate Transporter 1 antibodyAnti-Gibbon Ape Leukemia Virus Receptor 1 antibodyAnti-Glvr-1 antibodyAnti-Leukemia Virus Receptor 1 Homolog antibodyAnti-Phosphate Transporter 1 antibodyAnti-Pit-1 antibodyAnti-Solute Carrier Family 20 Member 1 antibodyAnti-SLC20A1 antibodyAnti-GLVR1 antibodyAnti-PIT1 antibody |
Information sourced from Uniprot.org