Anti-SLC20A1 antibody (257-356) (STJ25561)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SLC20A1 (257-356) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:200-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SLC20A1 |
| Gene ID | 6574 |
| Uniprot ID | S20A1_HUMAN |
| Immunogen Region | 257-356 |
| Immunogen Sequence | KIEREIKCSPSESPLMEKKN SLKEDHEETKLSVGDIENKH PVSEVGPATVPLQAVVEERT VSFKLGDLEEAPERERLPSV DLKEETSIDSTVNGAVQLPN |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 257-356 of human SLC20A1 (NP_005406.3). |
Additional Info
| Tissue Specificity | Ubiquitously expressed. |
| Function | Sodium-phosphate symporter which preferentially transports the monovalent form of phosphate with a stoichiometry of two sodium ions per phosphate ion. May play a role in extracellular matrix and cartilage calcification as well as in vascular calcification. Essential for cell proliferation but this function is independent of its phosphate transporter activity. (Microbial infection) May function as a retroviral receptor as it confers human cells susceptibility to infection to Gibbon Ape Leukemia Virus (GaLV), Simian sarcoma-associated virus (SSAV) and Feline leukemia virus subgroup B (FeLV-B) as well as 10A1 murine leukemia virus (10A1 MLV). |
| Protein Name | Sodium-Dependent Phosphate Transporter 1Gibbon Ape Leukemia Virus Receptor 1Glvr-1Leukemia Virus Receptor 1 HomologPhosphate Transporter 1Pit-1Solute Carrier Family 20 Member 1 |
| Database Links | Reactome: R-HSA-427652 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Sodium-Dependent Phosphate Transporter 1 antibodyAnti-Gibbon Ape Leukemia Virus Receptor 1 antibodyAnti-Glvr-1 antibodyAnti-Leukemia Virus Receptor 1 Homolog antibodyAnti-Phosphate Transporter 1 antibodyAnti-Pit-1 antibodyAnti-Solute Carrier Family 20 Member 1 antibodyAnti-SLC20A1 antibodyAnti-GLVR1 antibodyAnti-PIT1 antibody |
Information sourced from Uniprot.org