• Immunohistochemistry of rat Cortex with Anti-SLC1A2 primary antibody (STJ503050) at 1:100 dilution in Buffer. Section was treated with DAB and Haematoxylin stain. Magnification is at 40X.

Anti-SLC1A2 antibody (550-574) (STJ503050)

SKU:
STJ503050-100

£441.50
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Host: Rabbit
Applications: ELISA/IHC/IP/WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-SLC1A2 (550-574) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Purification: Affinity Purified
Concentration: 0.54 µg/µl
Dilution Range: WB: 1:500
DB: 1:10, 000
ELISA: 1:10, 000
IP: 1:200
IHC: 1:50-1:150
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: SLC1A2
Gene ID: 6506
Uniprot ID: EAA2_HUMAN
Immunogen Region: 550-574
Specificity: Will not cross react with EAAT1 protein.
Immunogen: Synthetic peptide corresponding to C terminal amino acids 550-574 of Human EAAT2.
Post Translational Modifications Glycosylated. Palmitoylation at Cys-38 is not required for correct subcellular localization, but is important for glutamate uptake activity.
Function Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion. Mediates Cl(-) flux that is not coupled to amino acid transport.this avoids the accumulation of negative charges due to aspartate and Na(+) symport. Essential for the rapid removal of released glutamate from the synaptic cleft, and for terminating the postsynaptic action of glutamate.
Protein Name Excitatory Amino Acid Transporter 2
Glutamate/Aspartate Transporter Ii
Sodium-Dependent Glutamate/Aspartate Transporter 2
Solute Carrier Family 1 Member 2
Database Links Reactome: R-HSA-210455
Reactome: R-HSA-210500
Reactome: R-HSA-425393
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Excitatory Amino Acid Transporter 2 antibody
Anti-Glutamate/Aspartate Transporter Ii antibody
Anti-Sodium-Dependent Glutamate/Aspartate Transporter 2 antibody
Anti-Solute Carrier Family 1 Member 2 antibody
Anti-SLC1A2 antibody
Anti-EAAT2 antibody
Anti-GLT1 antibody

Information sourced from Uniprot.org

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