Anti-SLC16A3 antibody (410-465) (STJ112566)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal MCT4/SLC16A3 (410-465) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SLC16A3 |
| Gene ID | 9123 |
| Uniprot ID | MOT4_HUMAN |
| Immunogen Region | 410-465 |
| Immunogen Sequence | IRKKPKEPQPEVAAAEEEKL HKPPADSGVDLREVEHFLKA EPEKNGEVVHTPETSV |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 410-465 of human MCT4/SLC16A3 (NP_004198.1). |
Additional Info
| Tissue Specificity | Highly expressed in skeletal muscle. |
| Function | Proton-dependent transporter of monocarboxylates such as L-lactate and pyruvate. Plays a predominant role in L-lactate efflux from highly glycolytic cells. |
| Protein Name | Monocarboxylate Transporter 4Mct 4Solute Carrier Family 16 Member 3 |
| Database Links | Reactome: R-HSA-210991Reactome: R-HSA-433692 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinBasolateral Cell MembranePlasma Membrane Localization Is Dependent Upon The Bsg/Mct4 InteractionBasolateral Sorting Signals (Blss) In C-Terminal Cytoplasmic Tail Ensure Its Basolateral Expression In Polarised Epithelial Cells |
| Alternative Antibody Names | Anti-Monocarboxylate Transporter 4 antibodyAnti-Mct 4 antibodyAnti-Solute Carrier Family 16 Member 3 antibodyAnti-SLC16A3 antibodyAnti-MCT3 antibodyAnti-MCT4 antibody |
Information sourced from Uniprot.org