| Host: | Rabbit |
| Applications: | IHC/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-SLC16A2 (10-60 aa) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Lyophilised |
| Purification: | IgG purified |
| Dilution Range: | IHC, WB. A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Storage Instruction: | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: | SLC16A2 |
| Gene ID: | 6567 |
| Uniprot ID: | MOT8_HUMAN |
| Immunogen Region: | 10-60 aa |
| Specificity: | Specific for SLC16A2. |
| Immunogen: | A synthetic peptide from aa region 10-60 of human SLC16A2 conjugated to blue carrier protein was used as the antigen. |
| Function | Specific thyroid hormone transmembrane transporter, that mediates both uptake and efflux of thyroid hormones across the cell membrane independently of pH or a Na(+) gradient. Major substrates are the iodothyronines T3 and T4 and to a lesser extent rT3 and 3,3-diiodothyronine (3,3'-T2). Acts as an important mediator of thyroid hormone transport, especially T3, through the blood-brain barrier (Probable). |
| Protein Name | Monocarboxylate Transporter 8Mct 8Monocarboxylate Transporter 7Mct 7Solute Carrier Family 16 Member 2X-Linked Pest-Containing Transporter |
| Database Links | Reactome: R-HSA-879518 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinApical Cell Membrane |
| Alternative Antibody Names | Anti-Monocarboxylate Transporter 8 antibodyAnti-Mct 8 antibodyAnti-Monocarboxylate Transporter 7 antibodyAnti-Mct 7 antibodyAnti-Solute Carrier Family 16 Member 2 antibodyAnti-X-Linked Pest-Containing Transporter antibodyAnti-SLC16A2 antibodyAnti-MCT7 antibodyAnti-MCT8 antibodyAnti-XPCT antibody |
Information sourced from Uniprot.org