| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Protein cornichon homolog 2 (10-60 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CNIH2 |
| Gene ID: |
254263 |
| Uniprot ID: |
CNIH2_HUMAN |
| Immunogen Region: |
10-60 aa |
| Specificity: |
This antibody detects endogenous levels of CNIH2 at Human/Mouse/Rat |
| Immunogen: |
Synthesized peptide derived from the human CNIH2 at the amino acid range 10-60 |
| Function | Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by regulating their rates of activation, deactivation and desensitization. Blocks CACNG8-mediated resensitization of AMPA receptors. |
| Protein Name | Protein Cornichon Homolog 2Cnih-2Cornichon Family Ampa Receptor Auxiliary Protein 2Cornichon-Like Protein |
| Database Links | Reactome: R-HSA-204005Reactome: R-HSA-5694530 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane ProteinPostsynaptic Cell MembraneCell ProjectionDendriteDendritic SpinePostsynaptic DensityAlso Localizes To The Cell Membrane Of Extrasynaptic Sites (Dendritic ShaftsSpines Of Pyramidal Cells) |
| Alternative Antibody Names | Anti-Protein Cornichon Homolog 2 antibodyAnti-Cnih-2 antibodyAnti-Cornichon Family Ampa Receptor Auxiliary Protein 2 antibodyAnti-Cornichon-Like Protein antibodyAnti-CNIH2 antibodyAnti-CNIL antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
