| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Na+/citrate cotransporter (313-363 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SLC13A5 |
| Gene ID: |
284111 |
| Uniprot ID: |
S13A5_HUMAN |
| Immunogen Region: |
313-363 aa |
| Specificity: |
This antibody detects endogenous levels of S13A5 at Human/Mouse/Rat |
| Immunogen: |
Synthesized peptide derived from the human S13A5 at the amino acid range 313-363 |
| Function | High-affinity sodium/citrate cotransporter that mediates the entry of citrate into cells, which is a critical participant of biochemical pathways. May function in various metabolic processes in which citrate has a critical role such as energy production (Krebs cycle), fatty acid synthesis, cholesterol synthesis, glycolysis, and gluconeogenesis. Transports citrate into the cell in a Na(+)-dependent manner, recognizing the trivalent form of citrate (physiological pH) rather than the divalent form. Can recognize succinate as a substrate, but its affinity for succinate is several fold lower than for citrate. The stoichiometry is probably 4 Na(+) for each carboxylate, irrespective of whether the translocated substrate is divalent or trivalent, rendering the process electrogenic. Involved in the regulation of citrate levels in the brain. |
| Protein Name | Na(+/Citrate CotransporterNactSodium-Coupled Citrate TransporterSodium-Dependent Citrate TransporterSolute Carrier Family 13 Member 5 |
| Database Links | Reactome: R-HSA-433137 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Na(+/Citrate Cotransporter antibodyAnti-Nact antibodyAnti-Sodium-Coupled Citrate Transporter antibodyAnti-Sodium-Dependent Citrate Transporter antibodyAnti-Solute Carrier Family 13 Member 5 antibodyAnti-SLC13A5 antibodyAnti-NACT antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
