Anti-SLC13A5 antibody (313-363 aa) (STJ193617)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human S13A5 at the amino acid range 313-363
General Information
| Short Description | Rabbit polyclonal anti-Na+/citrate cotransporter (313-363 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SLC13A5 |
| Gene ID | 284111 |
| Uniprot ID | S13A5_HUMAN |
| Immunogen | Synthesized peptide derived from the human S13A5 at the amino acid range 313-363 |
| Immunogen Region | 313-363 aa |
| Specificity | This antibody detects endogenous levels of S13A5 at Human/Mouse/Rat |
Additional Info
| Function | High-affinity sodium/citrate cotransporter that mediates the entry of citrate into cells, which is a critical participant of biochemical pathways. May function in various metabolic processes in which citrate has a critical role such as energy production (Krebs cycle), fatty acid synthesis, cholesterol synthesis, glycolysis, and gluconeogenesis. Transports citrate into the cell in a Na(+)-dependent manner, recognizing the trivalent form of citrate (physiological pH) rather than the divalent form. Can recognize succinate as a substrate, but its affinity for succinate is several fold lower than for citrate. The stoichiometry is probably 4 Na(+) for each carboxylate, irrespective of whether the translocated substrate is divalent or trivalent, rendering the process electrogenic. Involved in the regulation of citrate levels in the brain. |
| Protein Name | Na(+/Citrate CotransporterNactSodium-Coupled Citrate TransporterSodium-Dependent Citrate TransporterSolute Carrier Family 13 Member 5 |
| Database Links | Reactome: R-HSA-433137 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Na(+/Citrate Cotransporter antibodyAnti-Nact antibodyAnti-Sodium-Coupled Citrate Transporter antibodyAnti-Sodium-Dependent Citrate Transporter antibodyAnti-Solute Carrier Family 13 Member 5 antibodyAnti-SLC13A5 antibodyAnti-NACT antibody |
Information sourced from Uniprot.org