Anti-SLC12A7 antibody (STJA0008717)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human KCC4/SLC12A7
General Information
| Short Description | Rabbit polyclonal anti-Solute carrier family 12 member 7 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SLC12A7 |
| Gene ID | 10723 |
| Uniprot ID | S12A7_HUMAN |
| Immunogen | Synthesized peptide derived from human KCC4/SLC12A7 |
| Specificity | This antibody detects endogenous levels of KCC4/SLC12A7 at Human, Mouse, Rat |
Additional Info
| Function | Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May mediate K(+) uptake into Deiters' cells in the cochlea and contribute to K(+) recycling in the inner ear. Important for the survival of cochlear outer and inner hair cells and the maintenance of the organ of Corti. May be required for basolateral Cl(-) extrusion in the kidney and contribute to renal acidification. |
| Protein Name | Solute Carrier Family 12 Member 7Electroneutral Potassium-Chloride Cotransporter 4K-Cl Cotransporter 4 |
| Database Links | Reactome: R-HSA-426117 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Solute Carrier Family 12 Member 7 antibodyAnti-Electroneutral Potassium-Chloride Cotransporter 4 antibodyAnti-K-Cl Cotransporter 4 antibodyAnti-SLC12A7 antibodyAnti-KCC4 antibody |
Information sourced from Uniprot.org