Anti-SLC12A4 antibody (2-50 aa) (STJ13102275)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from aa region 2-50 of human SLC12A4 conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat and mouse.
General Information
| Short Description | Rabbit polyclonal anti-SLC12A4 (2-50 aa) for use in IHC and WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB (confirmed by recombinant protein). A dilution of 1: 200 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | SLC12A4 |
| Gene ID | 6560 |
| Uniprot ID | S12A4_HUMAN |
| Immunogen | A synthetic peptide from aa region 2-50 of human SLC12A4 conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat and mouse. |
| Immunogen Region | 2-50 aa |
| Specificity | Specific for SLC12A4. |
Additional Info
| Post Translational Modifications | Phosphorylated, phosphorylation may regulate transporter activity. |
| Function | Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May contribute to cell volume homeostasis in single cells. May be involved in the regulation of basolateral Cl(-) exit in NaCl absorbing epithelia. Isoform 4: No transporter activity. |
| Protein Name | Solute Carrier Family 12 Member 4Electroneutral Potassium-Chloride Cotransporter 1Erythroid K-Cl Cotransporter 1Hkcc1 |
| Database Links | Reactome: R-HSA-426117 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Solute Carrier Family 12 Member 4 antibodyAnti-Electroneutral Potassium-Chloride Cotransporter 1 antibodyAnti-Erythroid K-Cl Cotransporter 1 antibodyAnti-Hkcc1 antibodyAnti-SLC12A4 antibodyAnti-KCC1 antibody |
Information sourced from Uniprot.org