Anti-SLC10A2 antibody (280-335 aa) (STJ13102228)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from aa region 280-335 of human SLC10A2 conjugated to an immunogenic carrier protein was used as the antigen.
General Information
| Short Description | Rabbit polyclonal anti-SLC10A2 (280-335 aa) for use in IHC and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB. A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | SLC10A2 |
| Gene ID | 6555 |
| Uniprot ID | NTCP2_HUMAN |
| Immunogen | A synthetic peptide from aa region 280-335 of human SLC10A2 conjugated to an immunogenic carrier protein was used as the antigen. |
| Immunogen Region | 280-335 aa |
| Specificity | Specific for SLC10A2. |
Additional Info
| Function | Plays a critical role in the sodium-dependent reabsorption of bile acids from the lumen of the small intestine. Transports various bile acids, unconjugated or conjugated, such as cholate and taurocholate. Also responsible for bile acid transport in the renal proximal tubules, a salvage mechanism that helps conserve bile acids (Probable). Works collaboratively with the Na(+)-taurocholate cotransporting polypeptide (NTCP), the organic solute transporter (OST), and the bile salt export pump (BSEP), to ensure efficacious biological recycling of bile acids during enterohepatic circulation. |
| Protein Name | Ileal Sodium/Bile Acid CotransporterApical Sodium-Dependent Bile Acid TransporterAsbtIleal Na(+/Bile Acid CotransporterIleal Sodium-Dependent Bile Acid TransporterIbatIsbtNa(+-Dependent Ileal Bile Acid TransporterSodium/Taurocholate Cotransporting Polypeptide - IlealSolute Carrier Family 10 Member 2 |
| Database Links | Reactome: R-HSA-159418 |
| Cellular Localisation | MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Ileal Sodium/Bile Acid Cotransporter antibodyAnti-Apical Sodium-Dependent Bile Acid Transporter antibodyAnti-Asbt antibodyAnti-Ileal Na(+/Bile Acid Cotransporter antibodyAnti-Ileal Sodium-Dependent Bile Acid Transporter antibodyAnti-Ibat antibodyAnti-Isbt antibodyAnti-Na(+-Dependent Ileal Bile Acid Transporter antibodyAnti-Sodium/Taurocholate Cotransporting Polypeptide - Ileal antibodyAnti-Solute Carrier Family 10 Member 2 antibodyAnti-SLC10A2 antibodyAnti-ASBT antibodyAnti-ISBT antibodyAnti-NTCP2 antibody |
Information sourced from Uniprot.org