Anti-SLC10A1 nanobody [SAA1145] (STJN000272)

Anti-SLC10A1 nanobody [SAA1145] (STJN000272)

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STJN000272
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Covered by St John's Laboratory Guarantee

Host: Alpaca
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Alpaca monoclonal nanobody anti-Hepatic Sodium/Bile Acid Cotransporter is suitable for use in ELISA research applications.
Clonality : Monoclonal
Clone ID : SAA1145
Conjugation: Unconjugated
Isotype: VHH-8His-Cys-tag
Formulation: 0.01M PBS, pH 7.4.
Purification: Purified by Nickel column.
Concentration: 1 mg/mL
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term.
Gene Symbol: SLC10A1
Gene ID: 6554
Uniprot ID: NTCP_HUMAN
Function As a major transporter of conjugated bile salts from plasma into the hepatocyte, it plays a key role in the enterohepatic circulation of bile salts necessary for the solubilization and absorption of dietary fat and fat-soluble vitamins. It is strictly dependent on the extracellular presence of sodium. It exhibits broad substrate specificity and transports various bile acids, such as taurocholate, cholate, as well as non-bile acid organic compounds, such as estrone sulfate. Works collaboratively with the ileal transporter (NTCP2), the organic solute transporter (OST), and the bile salt export pump (BSEP), to ensure efficacious biological recycling of bile acids during enterohepatic circulation. (Microbial infection) Acts as a receptor for hepatitis B virus.
Protein Name Hepatic Sodium/Bile Acid Cotransporter
Cell Growth-Inhibiting Gene 29 Protein
Na(+/Bile Acid Cotransporter
Na(+/Taurocholate Transport Protein
Sodium/Taurocholate Cotransporting Polypeptide
Ntcp
Solute Carrier Family 10 Member 1
Slc10a1
Database Links Reactome: R-HSA-159418
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Nanobody Names Anti-Hepatic Sodium/Bile Acid Cotransporter nanobody
Anti-Cell Growth-Inhibiting Gene 29 Protein nanobody
Anti-Na(+/Bile Acid Cotransporter nanobody
Anti-Na(+/Taurocholate Transport Protein nanobody
Anti-Sodium/Taurocholate Cotransporting Polypeptide nanobody
Anti-Ntcp nanobody
Anti-Solute Carrier Family 10 Member 1 nanobody
Anti-Slc10a1 nanobody
Anti-SLC10A1 nanobody
Anti-NTCP nanobody
Anti-GIG29 nanobody

Information sourced from Uniprot.org

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