Anti-SLA antibody (STJ191472)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from part of the human protein
General Information
| Short Description | Rabbit polyclonal anti-Src-like-adapter for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SLA |
| Gene ID | 6503 |
| Uniprot ID | SLAP1_HUMAN |
| Immunogen | Synthesized peptide derived from part of the human protein |
| Specificity | SLAP1 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Adapter protein, which negatively regulates T-cell receptor (TCR) signaling. Inhibits T-cell antigen-receptor induced activation of nuclear factor of activated T-cells. Involved in the negative regulation of positive selection and mitosis of T-cells. May act by linking signaling proteins such as ZAP70 with CBL, leading to a CBL dependent degradation of signaling proteins. |
| Protein Name | Src-Like-AdapterSrc-Like-Adapter Protein 1Slap-1Hslap |
| Database Links | Reactome: R-HSA-9706369 |
| Cellular Localisation | CytoplasmEndosomeColocalizes With Endosomes |
| Alternative Antibody Names | Anti-Src-Like-Adapter antibodyAnti-Src-Like-Adapter Protein 1 antibodyAnti-Slap-1 antibodyAnti-Hslap antibodyAnti-SLA antibodyAnti-SLAP antibodyAnti-SLAP1 antibody |
Information sourced from Uniprot.org