Anti-SIX5 antibody (201-250 aa) (STJ95673)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human SIX5 at the amino acid range 201-250
General Information
| Short Description | Rabbit polyclonal anti-Homeobox protein SIX5 (201-250 aa) for use in WB and IHC in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC-P 1:50-300 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SIX5 |
| Gene ID | 147912 |
| Uniprot ID | SIX5_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human SIX5 at the amino acid range 201-250 |
| Immunogen Region | 201-250 aa |
| Specificity | Six5 Polyclonal Antibody detects endogenous levels of Six5 protein. |
Additional Info
| Function | Transcription factor that is thought to be involved in regulation of organogenesis. May be involved in determination and maintenance of retina formation. Binds a 5'-GGTGTCAG-3' motif present in the ARE regulatory element of ATP1A1. Binds a 5'-TCAAGAGTTNC-3' motif present in the MEF3 element in the myogenin promoter, and in the IGFBP5 promoter. Thought to be regulated by association with Dach and Eya proteins, and seems to be coactivated by EYA1, EYA2 and EYA3. |
| Protein Name | Homeobox Protein Six5Dm Locus-Associated Homeodomain ProteinSine Oculis Homeobox Homolog 5 |
| Database Links | |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Homeobox Protein Six5 antibodyAnti-Dm Locus-Associated Homeodomain Protein antibodyAnti-Sine Oculis Homeobox Homolog 5 antibodyAnti-SIX5 antibodyAnti-DMAHP antibody |
Information sourced from Uniprot.org