Anti-ASB9 antibody (169-219 aa) (STJ194602)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human ASB9 at the amino acid range 169-219
General Information
| Short Description | Rabbit polyclonal anti-Ankyrin repeat and SOCS box protein 9 (169-219 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ASB9 |
| Gene ID | 140462 |
| Uniprot ID | ASB9_HUMAN |
| Immunogen | Synthesized peptide derived from the human ASB9 at the amino acid range 169-219 |
| Immunogen Region | 169-219 aa |
| Specificity | This antibody detects endogenous levels of ASB9 at Human/Mouse |
Additional Info
| Function | Substrate-recognition component of a cullin-5-RING E3 ubiquitin-protein ligase complex (ECS complex, also named CRL5 complex), which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. The ECS(ASB9) complex catalyzes ubiquitination of creatine kinases CKB and CKMT1A. Isoform 2: Does not interact with the Elongin BC complex, likely to be a negative regulator of isoform 1. |
| Protein Name | Ankyrin Repeat And Socs Box Protein 9Asb-9 |
| Database Links | Reactome: R-HSA-8951664Reactome: R-HSA-983168 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Ankyrin Repeat And Socs Box Protein 9 antibodyAnti-Asb-9 antibodyAnti-ASB9 antibody |
Information sourced from Uniprot.org