Anti-SIGLECL1 antibody (C-Term) (STJ70318)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-SIGLECL1 (C-Term) is suitable for use in ELISA research applications. |
| Applications | Pep-ELISA |
| Host | Goat |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:128000.WB: Preliminary experiments gave no signal but low background in Human PBMC and Molt-4 lysates at up to 1ยตg/ml. We would appreciate any feedback from people in the field-have any results |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20ยฐC on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | SIGLEC12 |
| Gene ID | 89858 |
| Uniprot ID | SIG12_HUMAN |
| Accession Number | NP_201586.1; NP_443729.1 |
| Immunogen Region | C-Term |
| Immunogen Sequence | EAIGYEYSEINIPK |
| Specificity | This antibody is expected to recognise both human isoforms of this protein (NP_201586.1; NP_443729.1). |
Additional Info
| Function | Putative adhesion molecule that mediates sialic-acid dependent binding to cells. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. |
| Protein Name | Sialic Acid-Binding Ig-Like Lectin 12Siglec-12Sialic Acid-Binding Ig-Like Lectin-Like 1Siglec-L1 |
| Database Links | Reactome: R-HSA-198933 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Sialic Acid-Binding Ig-Like Lectin 12 antibodyAnti-Siglec-12 antibodyAnti-Sialic Acid-Binding Ig-Like Lectin-Like 1 antibodyAnti-Siglec-L1 antibodyAnti-SIGLEC12 antibodyAnti-SIGLECL1 antibodyAnti-SLG antibodyAnti-UNQ9215 antibodyAnti-PRO34042 antibody |
Information sourced from Uniprot.org