Anti-SIGLEC8/SAF-2 antibody [SAA0177] {FITC} (STJA0028797)

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STJA0028797-100
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Short Description :Human monoclonal Sialic Acid-Binding Ig-Like Lectin 8 antibody for use in FC in human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:FC
Host:Human
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :SAA0177
Isotype:IgG1k
Conjugation:FITC
Concentration:0.5 mg/mL
Purification:Purified
Formulation:PBS pH 7.4, 50% glycerol, 0.05% proclin300
Storage Instruction:Store at 4°C for 12 months. Protect from light. Do not freeze.
Gene Symbol:SIGLEC8
Gene ID:27181
Uniprot ID:SIGL8_HUMAN
Function Putative adhesion molecule that mediates sialic-acid dependent binding to blood cells. Preferentially binds to alpha-2,3-linked sialic acid. Also binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. Recognizes simultaneously epitopes having a terminal N-acetylneuraminic acid (sialic acid) and an underlying 6-O-sulfated galactose. Preferentially binds to Gal-6-sulfated sialyl-Lewis X glycan epitopes.
Protein Name Sialic Acid-Binding Ig-Like Lectin 8
Siglec-8
Sialoadhesin Family Member 2
Saf-2
Database Links Reactome: R-HSA-198933
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Sialic Acid-Binding Ig-Like Lectin 8 antibody
Anti-Siglec-8 antibody
Anti-Sialoadhesin Family Member 2 antibody
Anti-Saf-2 antibody
Anti-SIGLEC8 antibody
Anti-SAF2 antibody

Information sourced from Uniprot.org

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