• Western blot analysis of lysate from K562 cells, using SIGLEC7 Antibody.
  • Immunohistochemical analysis of paraffin-embedded human-colon-cancer, antibody was diluted at 1:100
  • Immunohistochemical analysis of paraffin-embedded human-colon-cancer, antibody was diluted at 1:100
  • Immunohistochemical analysis of paraffin-embedded human-colon-cancer, antibody was diluted at 1:100
  • Western blot analysis of K562 cells using CD328 Polyclonal Antibody.. Secondary antibody was diluted at 1:20000

Anti-SIGLEC7 antibody (51-100 aa) (STJ96646)

SKU:
STJ96646

€60.00 - €315.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Sialic acid-binding Ig-like lectin 7 (51-100 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC-P 1:100-300
ELISA 1:20000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SIGLEC7
Gene ID: 27036
Uniprot ID: SIGL7_HUMAN
Immunogen Region: 51-100 aa
Specificity: CD328 Polyclonal Antibody detects endogenous levels of CD328 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human SIGLEC7 at the amino acid range 51-100
Post Translational Modifications Tyrosine phosphorylated.
Function Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- and alpha-2,6-linked sialic acid. Also binds disialogangliosides (disialogalactosyl globoside, disialyl lactotetraosylceramide and disialyl GalNAc lactotetraoslylceramide). The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Mediates inhibition of natural killer cells cytotoxicity. May play a role in hemopoiesis. Inhibits differentiation of CD34+ cell precursors towards myelomonocytic cell lineage and proliferation of leukemic myeloid cells (in vitro).
Protein Name Sialic Acid-Binding Ig-Like Lectin 7
Siglec-7
Adhesion Inhibitory Receptor Molecule 1
Airm-1
Cdw328
D-Siglec
Qa79 Membrane Protein
P75
Cd Antigen Cd328
Database Links Reactome: R-HSA-198933
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Sialic Acid-Binding Ig-Like Lectin 7 antibody
Anti-Siglec-7 antibody
Anti-Adhesion Inhibitory Receptor Molecule 1 antibody
Anti-Airm-1 antibody
Anti-Cdw328 antibody
Anti-D-Siglec antibody
Anti-Qa79 Membrane Protein antibody
Anti-P75 antibody
Anti-Cd Antigen Cd328 antibody
Anti-SIGLEC7 antibody
Anti-AIRM1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance