Anti-SIGLEC6 antibody (Internal) (STJ72320)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-SIGLEC6 (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB |
| Host | Goat |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:16000.WB: Experiments gave bands at approx 60kDa and 35kDa in Human Placenta lysates. These bands correspond to earlier findings with different antibodies from other sources. This protein has a |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | SIGLEC6 |
| Gene ID | 946 |
| Uniprot ID | SIGL6_HUMAN |
| Accession Number | NP_001236.4; NP_942142.3; NP_942143.3 |
| Immunogen Region | Internal |
| Immunogen Sequence | KWMKYGYTSSK |
| Specificity | This antibody is expected to recognize all reported isoforms (NP_001236.4; NP_942142.3; NP_942143.3). |
Additional Info
| Function | Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. |
| Protein Name | Sialic Acid-Binding Ig-Like Lectin 6Siglec-6Cd33 Antigen-Like 1Cdw327Obesity-Binding Protein 1Ob-Bp1Cd Antigen Cd327 |
| Database Links | Reactome: R-HSA-198933 |
| Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 2: Secreted |
| Alternative Antibody Names | Anti-Sialic Acid-Binding Ig-Like Lectin 6 antibodyAnti-Siglec-6 antibodyAnti-Cd33 Antigen-Like 1 antibodyAnti-Cdw327 antibodyAnti-Obesity-Binding Protein 1 antibodyAnti-Ob-Bp1 antibodyAnti-Cd Antigen Cd327 antibodyAnti-SIGLEC6 antibodyAnti-CD33L antibodyAnti-CD33L1 antibodyAnti-OBBP1 antibody |
Information sourced from Uniprot.org