Anti-SIGLEC12 antibody (20-210) (STJ110817)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SIGLEC12 (20-210) antibody for use in WB and ELISA in mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SIGLEC12 |
| Gene ID | 89858 |
| Uniprot ID | SIG12_HUMAN |
| Immunogen Region | 20-210 |
| Immunogen Sequence | EQKDYLLTMQKSVTVQEGLC VSVLCSFSYPQNGWTASDPV HGYWFRAGDHVSRNIPVATN NPARAVQEETRDRFHLLGDP QNKDCTLSIRDTRESDAGTY VFCVERGNMKWNYKYDQLSV NVTASQDLLSRYRLEVPESV TVQEGLCVSVPCSVLYPHYN WTASSPVYGSWFKEGADIPW DIPVATNTPSG |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 20-210 of human SIGLEC12 (NP_443729.1). |
Additional Info
| Tissue Specificity | Isoform Short is highly expressed in spleen, small intestine and adrenal gland.it is lower expressed in thyroid, placenta, brain, stomach, bone marrow, spinal cord and breast. Isoform Long is highly expressed in spleen, small intestine and bone marrow.it is lower expressed in thyroid, placenta, thymus, trachea, stomach, lung, adrenal gland, fetal brain and testis. |
| Function | Putative adhesion molecule that mediates sialic-acid dependent binding to cells. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. |
| Protein Name | Sialic Acid-Binding Ig-Like Lectin 12Siglec-12Sialic Acid-Binding Ig-Like Lectin-Like 1Siglec-L1 |
| Database Links | Reactome: R-HSA-198933 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Sialic Acid-Binding Ig-Like Lectin 12 antibodyAnti-Siglec-12 antibodyAnti-Sialic Acid-Binding Ig-Like Lectin-Like 1 antibodyAnti-Siglec-L1 antibodyAnti-SIGLEC12 antibodyAnti-SIGLECL1 antibodyAnti-SLG antibodyAnti-UNQ9215 antibodyAnti-PRO34042 antibody |
Information sourced from Uniprot.org