| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal anti-SH3 domain-containing protein 19 for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SH3D19 |
| Gene ID: | 152503 |
| Uniprot ID: | SH319_HUMAN |
| Specificity: | This antibody detects endogenous levels of SH3D19 at Human, Mouse |
| Immunogen: | Synthesized peptide derived from human SH3D19 |
| Function | May play a role in regulating A disintegrin and metalloproteases (ADAMs) in the signaling of EGFR-ligand shedding. May be involved in suppression of Ras-induced cellular transformation and Ras-mediated activation of ELK1. Plays a role in the regulation of cell morphology and cytoskeletal organization. |
| Protein Name | Sh3 Domain-Containing Protein 19Adam-Binding Protein Eve-1Een-Binding ProteinEbp |
| Database Links | Reactome: R-HSA-432722 |
| Cellular Localisation | CytoplasmNucleusIs Recruited To The Nucleus By The Kmt2a/Mll1-Een Fusion Protein |
| Alternative Antibody Names | Anti-Sh3 Domain-Containing Protein 19 antibodyAnti-Adam-Binding Protein Eve-1 antibodyAnti-Een-Binding Protein antibodyAnti-Ebp antibodyAnti-SH3D19 antibody |
Information sourced from Uniprot.org
