Anti-SH2D4A antibody (Internal) (STJ71789)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-SH2D4A (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB |
| Host | Goat |
| Reactivity | Human/Dog |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:1000.WB: Approx. 55kDa band observed in Human Kidney lysates (calculated MW of 52.7kDa according to NP_071354.2). Recommended concentration: 0.1-0.3µg/ml. |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | SH2D4A |
| Gene ID | 63898 |
| Uniprot ID | SH24A_HUMAN |
| Accession Number | NP_071354.2 |
| Immunogen Region | Internal |
| Immunogen Sequence | HQKKESMKKKQDE |
Additional Info
| Function | Inhibits estrogen-induced cell proliferation by competing with PLCG for binding to ESR1, blocking the effect of estrogen on PLCG and repressing estrogen-induced proliferation. May play a role in T-cell development and function. |
| Protein Name | Sh2 Domain-Containing Protein 4aProtein Sh(2aProtein Phosphatase 1 Regulatory Subunit 38 |
| Cellular Localisation | CytoplasmLocated At Podocyte Foot Processes |
| Alternative Antibody Names | Anti-Sh2 Domain-Containing Protein 4a antibodyAnti-Protein Sh(2a antibodyAnti-Protein Phosphatase 1 Regulatory Subunit 38 antibodyAnti-SH2D4A antibodyAnti-PPP1R38 antibodyAnti-SH2A antibody |
Information sourced from Uniprot.org